I am reading about canny little entities that seem to have awesome fighting spirits and minds of their own, namely bacteria. For every new antibiotic that is designed to kill them, they try to figure out a defence strategy. It's like a very dangerous game of chess or a fencing match between an ill person and a bacterium, with death being a strong possibility for the loser.
They don't really have minds of their own of course, they just reproduce and evolve in a matter of hours and, if just one of the millions mutates to be resistant to the antibiotic during that process the descendents of it will flourish even though the rest of them perish. It's all very complicated but my piece of jolly good advice today is always finish off your course of antibiotics and don't wear pink shoes.